Jagat, the progressive world, is parivartate, changing. In so many ways they are changing. This is a fact.
Now how you can deny the living force behind this gigantic mechanical arrangement? Call it material world, material machine or whatever you may call. How you can deny? At least from your practical experience you cannot deny. You may put some jugglery of words, but the actual fact is this.
So duṣkṛtina means a person who does not believe in this. They are called miscreants. Paritrāṇāya sādhūnāṁ vināśāya ca duṣkṛtām (BG 4.8). So God, in His incarnation, appears with two missionary purposes. One purpose is paritrāṇāya sādhūnām, just to protect the pious who are obedient to the laws of God, or the laws of nature; and to vanquish persons who are disobedient. They are called duṣkṛtina.
This duṣkṛtina, or miscreant, is described in another place also in the Bhagavad-gītā: na māṁ duṣkṛtino mūḍhāḥ prapadyante narādhamāḥ (BG 7.15). The purport is, Kṛṣṇa says, that those who are miscreants, always disobeying the laws of nature or always denying the prime factor behind the wonderful activities of nature, such miscreants, na māṁ duṣkṛtino mūḍhāḥ (BG 7.15). Mūḍhāḥ means they are rascals. They cannot . . . they will put so many theories that "There is no God," and none of the theories are practical, neither they can prove it by experimental knowledge. Still, they will insist on. That is their business. And when we say . . . when somebody says, "You prove it," the answer is, "Well, we are advancing. Some day will come, we shall prove it." That's all. "Some day will come."
They do not understand that "Trust no future, however pleasant." Why you are expecting that some day will come when science will be perfect? Throughout the whole history of the human society, never it has been possible that one can give life. There is no such instance in the history. Janma-mṛtyu-jarā-vyādhi-duḥkha-doṣānudarśanam (BG 13.9). The four principles of material inebrieties, namely birth, death, old age and disease, nobody has been able to check it in the past history of human society, and how you can believe that in future these problems, namely janma-mṛtyu-jarā-vyādhi, birth, death, old age and disease, will be solved by the advancement of science? So at least we cannot believe. And no sane man will believe it.
Therefore those who are trying to defy the presence of God, saying: "God is dead," "There is no God," and trying to prove by so-called scientific method there is no God, the matter is working out of his own way, and things are taking place—there are so many theories—they are all classified as miscreant. Na māṁ duṣkṛtino mūḍhāḥ. Miscreants, and mūḍhāḥ, means rascal.