Prabhupāda: "Because I have entered into this universe by My plenary portion, therefore it is existing." It is explained in the Bhagavad-gītā.
So without spiritual touch, there is no question of matter working or expanding or growing. That is not possible. So in the seed of any tree, because there is that living entity, therefore it grows into a big tree. Every tree, they are also living entities, in a different form. So here also, in the creation, without the supreme living entity entering within the mahat-tattva, there is no possibility of creation. Go on.
Pradyumna: "And in each one of the universes the Lord enters as Garbhodakaśāyī Viṣṇu. In the Bhagavad-gītā it is also mentioned that the material world is created at certain intervals and then again destroyed. This creation and destruction is done by the supreme will because of the conditioned souls, or the nitya-baddha living entities. Nitya-baddha, or the eternally conditioned souls, have the sense of individuality or..."
Prabhupāda: (Hindi) Hmm? Yes.