In the Hari-bhakti-sudhodaya it is stated that when Prahlāda Mahārāj was thinking himself unfit to approach the Supreme Personality of Godhead, he immersed himself in great distress, in an ocean of unhappiness. As such, he used to shed tears and lie down on the floor as though unconscious.
The students of a great devotee once talked amongst themselves in this way: "My dear Godbrothers, our spiritual master, after seeing the lotus feet of the Lord, has thrown himself into the fire of lamentation, and because of this fire the water of his life has almost dried away. Let us now pour the nectar of the holy name through his ears, and by doing so the swan of his life may again show signs of life."
When Lord Kṛṣṇa went to the city of Śoṇitapura to fight with Bali's son Bāṇa and to cut off all his hands, Uddhava, being separated from Kṛṣṇa and thinking of His fight, was almost completely stunned into unconsciousness.
When a devotee is fully in love with the Supreme Personality of Godhead, there may be the following symptoms due to his feelings of separation from the Lord: feverish condition of the body, withering of the body, lack of sleep, nonattachment, inertness, appearing diseased, madness, unconsciousness and sometimes death.
As far as the feverish condition of the body is concerned, Uddhava once told Nārada, "My dear great sage, the lotus flower that is a friend of the sun may be a cause of distress for us; and the fire in the ocean may cause us some burning sensation; and Indīvara, the friend of a demon, may distress us in various ways—we do not mind. But the most regrettable factor is that all of them remind us of Kṛṣṇa, and this is giving us too much distress!" This is an instance of the feverish condition which is due to being separated from Kṛṣṇa.
Some of the devotees who went to see Kṛṣṇa at Dvārakā and were detained at the door said: "My dear Kṛṣṇa, O friend of the Pāṇḍus, as the swan loves to dive into the water amongst the lily flowers and would die if he were taken from the water, so we only wish to be with You. Our limbs are being shrunken and faded because You have been taken away from us."
The King of Bahulā, although very comfortably situated in his palace, began to think the nights very long and distressing because of his separation from Kṛṣṇa.
King Yudhiṣṭhira once said, "Kṛṣṇa, the chariot driver of Arjuna, is the only relative of mine within the three worlds. Therefore, my mind is becoming maddened day and night with separation from His lotus feet, and I do not know how to situate myself or where I shall go to attain any steadiness of mind." This is another example of lack of sleep.
Some of the cowherd friends of Kṛṣṇa said, "My dear Kṛṣṇa, O enemy of the Mura demon, just think of Your personal servant Raktaka. Simply because he saw a peacock feather he is now closing his eyes and is no longer attentive to pasturing the cows. Rather, he has left them in a faraway pasture and has not even bothered to use his stick to control them." This is an instance of mental imbalance due to separation from Kṛṣṇa.
When Lord Kṛṣṇa went to the capital of King Yudhiṣṭhira, Uddhava was so afflicted by the fire of separation from Śrī Kṛṣṇa that the perspiring water from his enflamed body and the tears from his eyes poured from him, and in this way he became completely stunned.
When Śrī Kṛṣṇa left the city of Dvārakā to seek out the Syamantaka jewel, He was late returning home. Uddhava became so afflicted that the symptoms of disease became manifest on his body. Actually, due to his excessive ecstatic love for Kṛṣṇa, Uddhava became known in Dvārakā as crazy. To his great fortune, on that day Uddhava's reputation as a crazy fellow was firmly established. Uddhava's craziness was practically proved when he went to Raivataka Hill to minutely observe the congested black clouds. In his disturbed condition, he began to pray to these clouds, and he expressed his jubilation by bowing down before them.
Uddhava informed Kṛṣṇa, "My dear leader of the Yadu dynasty, Your servants in Vṛndāvana cannot sleep at night thinking of You, so now they are all lying down on the bank of the Yamunā almost paralyzed. And it appears that they are almost dead because their breathing is very slow." This is an instance of becoming unconscious due to separation from Kṛṣṇa.