Prabhupāda: Kāma-karmabhiḥ. Avidyā-kāma-karmabhiḥ. They are creating a situation of suffering by unnecessary desire. That's all. So your scientific improvement means you are creating a situation of suffering. That's all. No improvement. You cannot. Kāma-karmabhiḥ, kāma-karmabhiḥ. They are working in such a way... Bhaktivinoda Ṭhākura also says the same thing: anitya saṁsāre moha janamiyā jībake karaye gādhā. The so-called scientific improvement means he's already an ass, and he's becoming more, better ass. That's all. Nothing more. He's already an ass because he's part and parcel of Kṛṣṇa, and he has come to this material world to enjoy. That is ass mentality. There is no enjoyment. So he's already an ass. And this scientific improvement means he's becoming more attached to this material world to remain better ass. Avidyā... anitya saṁsāre, anitya. He cannot stay here. Suppose, working very hard like an ass, he gets a skyscraper building, throughout his whole life, laboring. But he cannot stay there. He'll be kicked out. Is it not ass? Is he not an ass? He cannot stay there. Anitya saṁsāre. Anitya. Because it is not the permanent settlement. You are trying: dum dum. (sound imitation) Very strong foundation. That's all right. But your foundation is nothing. You'll be kicked out. Therefore he's an ass. That: "I'll stay here for twenty years." Why dum dum dum, foundation stone? Where is your foundation? Therefore he's an ass.
Svarūpa Dāmodara: Anitya is temporary, Prabhupāda?
Prabhupāda: Yes, anitya means temporary. You cannot stay here. That they do not understand. They're making research, making research. And if we ask them: "What you are doing?" "For the next generation, future." And what about your, your...? You're going to be a tree next life. What you'll do with your next generation? But he's ass. He does not know. He s going to stand before that skyscraper building, a tree, for ten thousand years, and he's making: dum dum dum. Therefore he's an ass. He does not know where he's going. And he's making provision for the next generation. What is the next generation? If there is no petrol, what you'll do, next generation? And how the next generation will help you? You are going to be a dog, cat or tree. So next generation, how he'll help you? Jībake karaye gādhā. Therefore he's an ass. He does not know his personal interest. And making research work. What research work? Simply śrama eva hi kevalam (SB 1.2.8). Simply laboring, what is called? Labor of love? Or what is that?
Devotee: Yes.
Prabhupāda: Therefore Bhāgavata says: bhave 'smin kliśyamānānām avidyā kāma-karmabhiḥ. Avidyā. Avidyā means ass, no intelligence. He does not know what is life, what is the course of life, how things are going on. He does not know. The more he is increasing his unnecessary desires, he's making himself entangled. That he does not know. He has to take freedom from the repetition of birth and death, but he's becoming more and more entangled. Avidyā kāma-karmabhiḥ. This is Bhāgavata. In one line, the whole material existence explained. This is literature. In one line, there is thousands years research work. In one line. Bhave 'smin. Now this bhave 'smin, you make research. Asmin, in this world, taking birth. So you have to learn so many things on these two words. How the living entities are taking birth in this world. Wherefrom he's coming, where he's going. What is his business. So many things in these two words. Bhave 'smin. Kliśyamānānām. Struggle for existence. Why? Avidyā. Ignorance. What is that avidyā? Kāma-karmabhiḥ.
Brahmānanda: Desire.
Prabhupāda: Activities of sense gratification. He's becoming entangled.