As soon as we become addicted to sinful activities, then our real, constitutional position we forget, and we become mad after it, and the disease increases. So here it is suggested that "According to the disease . . ." Diseases, there are different types of disease. Some disease is very acute; some disease is not very important. So he suggests that tasmāt purā eva ca iha pāpa-niṣkṛtau yateta mṛtyor avipadya ātmanā. You have to die. That is a fact. Nobody will live here. "As sure as death." So before death we must finish the atonement of our sinful activities. This is recommended. Purā. Tasmāt purā eva iha pāpa-niṣkṛtau. But nobody knows. At the present moment they do not know what is pāpa and how to get out of it; what is next birth. Everything is unknown at the present moment. This is the modern civilization.
Therefore Caitanya Mahāprabhu took one thing, that ceto-darpaṇa-mārjanam (CC Antya 20.12). They are in gross misunderstanding of life. So in order to cleanse their heart to understand what is the position, where they are going, where they are actually, how things are going on . . . It is due to ignorance. So Caitanya Mahāprabhu says that ceto-darpaṇa-mārjanam. Ceto-da . . . Bhava-mahā-dāvāgni-nirvā . . . Unless we cleanse our hearts of all the dirty things that you have accumulated, then we have to continue the sufferings of this material world. But if we cleanse, we understand what is our position.