Hṛdayānanda: (translating) Does the soul suffer with the mind, or he's always enjoying?
Prabhupāda: Yes, he creates. He's thinking in his own way; therefore he's creating a situation which will be botheration for him.
Hṛdayānanda: (translating) If we are so small, why is there a poison of the senses?
Prabhupāda: Poison? Yes, because we have come to the poisonous condition, the senses have become poisonous. Just like if you go to an area where there is infectious disease, you contaminate and suffer from the disease. So it is your duty not to go such a place where there is contamination. It is up to you. You create your own situation of suffering or enjoying. Yes.
Hṛdayānanda: (translating) She said if we have not already achieved perfection, then how can the soul achieve the perfection? It seems that he has to reincarnate slowly in time to achieve the perfection.
Prabhupāda: No, that is no argument. If you are diseased, you can be cured if you take the proper medicine, treatment. That's all. Disease is not hopelessness. Otherwise why the people go for treatment to a physician? Similarly, out of ignorance you are now in this miserable condition, but if you become treated by bona fide spiritual master, then you'll be cured. Originally every one of us—pure. Now, by material condition we are now contaminated. That... But there is process to get out of this material contamination. Then again we become pure. And as soon as we become pure, there is no more birth, death, old age, and disease. Finished.