One day Śrīmatī Rādhārāṇī was churning curd for Kṛṣṇa. At that time the jeweled bangles on Her hands were circling around, and She was also chanting the holy name of Kṛṣṇa. All of a sudden She thought, "I am chanting the holy name of Kṛṣṇa, and My superiors—My mother-in-law and My sister-in-law—may hear Me!" By this thought Rādhārāṇī became overanxious. This is an instance of feeling guilty because of devotion to Kṛṣṇa.
One day the beautiful-eyed Śrīmatī Rādhārāṇī entered into the forest to collect some flowers to prepare a garland for Kṛṣṇa. While collecting the flowers, She became afraid that someone might see Her, and She felt some fatigue and weakness. This is an instance of guilty feelings caused by labor for Kṛṣṇa.
There is a statement in Rasa-sudhākara that after passing the night with Kṛṣṇa, Rādhārāṇī became so weak that She was unable to get up from bed. When Kṛṣṇa took Her hand to help Her, Rādhārāṇī felt guilty about having passed the night with Him.
Fatigue
Fatigue is felt after walking a long distance, after dancing and after sex activity. In this kind of fatigue there is dizziness, perspiration, inactivity of the limbs, yawning and very heavy breathing.
One day Yaśodā was chasing Kṛṣṇa in the yard after He had offended Her. After a while Yaśodā became very fatigued, and therefore she was perspiring, and her bunched hair became loosened. This is an instance of becoming fatigued because of working too much.