This prayer is to the spiritual master. Ajñāna-timirāndhasya. Everyone born in this material world is in ignorance, born ignorant. We should take it for granted, this material world is called tamah. The Vedic injunction is tamasi mā jyotir gamaḥ: "Don't remain in this darkness; come to the light."
Actually, this material world is dark. It is lighted with sunlight, moonlight, electric light, this light, that light. Its nature is darkness. That is scientific fact. So anyone born in this material world, beginning from Brahma, the chief personality in the topmost planet of this universe, down to the ant—everyone is in darkness.
Therefore this prayer, ajñāna-timirāndhasya jñānāñjana-śalākayā. Everyone is put into the darkness, and one who opens the eyes by the torch of knowledge. Darkness means without knowledge. So it is the duty of the spiritual master to open the eyes of the person in darkness with torch of knowledge. Ajñāna-timirāndhasya jñānāñjana-śalākayā cakṣur unmīlitaṁ yena. The person who opens our eyes in that way, he is the spiritual master. And one may offer his respectful obeisances unto such personality.
So people should not be put into darkness, but they should be brought into light. Therefore in every human society, there is a sort of institution which is called religious institution. Take it for granted—Hinduism, Muslimism or Christianism or Buddhism—any "ism" you take—what is the purpose? The purpose is to bring the persons to the light. That is the purpose of religion. And what is that light? That light is the Supreme Personality of Godhead.
Religion means the codes of the Supreme Personality of Godhead. It is stated in the Śrīmad-Bhāgavatam, dharmaṁ tu sākṣād bhagavat-praṇītam (SB 6.3.19).
Just like in the state, there is king's law. The kings gives you some law, and if you are a good citizen, you are to obey those laws and you live peacefully. This is crude example. Similarly, dharma, or religion, means to obey the laws of God, that's all. It may be different according to time, circumstances, people. Just like laws in India, the state laws in India, may not agree cent percent with the laws of United States. But that does not mean there is no law. And one has to abide by the law. That is the general principle.